No one in The Silence of the Lambs found themselves walking in Memphis. The Shelby County Courthouse was actually part of a military museum on the campus of the University of Pittsburgh, many many miles from Beale Street. (Source) Like moths to a movie poster, movie fans love The Silence of the Lambs cover artwork for the poster.

In preparation for his role, Sir Anthony Hopkins studied files of serial killers. Also, he visited prisons, and studied convicted murderers, and was present during some court hearings concerning gruesome murderers and serial killings. The real-life FBI's Behavioral Science Unit assisted in the making of this movie.

Trivia: Anthony Hopkins won a Best Actor Oscar for his role as Hannibal Lecter, even though he's only on screen for 16 minutes. 42 Trivia: None of the moths seen in the film are actual Death Head moths.